Cast / Details
| Paul Giamatti | Ted Hedley (segment "1961") |
| Natasha Lyonne | Jeanne (segment "1972") |
| Elizabeth Perkins | Alice Hedley (segment "1961") |
| Jill Brennan | Nurse Betty (segment "1961") |
| C.J. Bates | Nurse Murphy (segment "1961") (as C J Bates) |
| Chloë Sevigny | Amy (segment "1972") |
| Heather McComb | Diane (segment "1972") |
| Amy Carlson | Michelle (segment "1972") |
| Rashida Jones | Feminist (segment "1972") |
| Kirk Trutner | Neighbor (segment "1972") |
| Jenny O'Hara | Marge Carpenter (segment "1961") |
| Kathy Najimy | Doctor (segment "2000") |
| Lisa Welti | Nurse Trish (segment "1961") |
| Susan Mosher | Nurse June (segment "1961") |
| Donald Elson | Sam (segment "1961") |
| Lee Garlington | Georgette (segment "1972") |
| Michelle Williams | Linda (segment "1972") |
| Sharon Stone | Fran (segment "2000") |
| Nia Long | Karen (segment "1972") |
| Ellen DeGeneres | Kal (segment "2000") |
| Marian Seldes | Abby Hedley (segment "1961") |
| Regina King | Allie (segment "2000") |
| Vanessa Redgrave | Edith Tree (segment "1961") |
| Marley McClean | Maggie Hedley (segment "1961") |
| Mitchell Anderson | Arnold (segment "2000") |