Blade: Trinity (2004)
| Wesley Snipes | Blade/Eric Brooks/The Daywalker |
| Jessica Biel | Abigail Whistler |
| Parker Posey | Danica Talos |
| Ryan Reynolds | Hannibal King |
| Natasha Lyonne | Sommerfield |
| Clay Cullen | Stone |
| John Ashker | Campbell |
| Steven McMichael | Denlinger |
| Eric Bogosian | Bentley Tittle |
| Christopher Heyerdahl | Caulder |
| Ron Selmour | Dex |
| Patton Oswalt | Hedges |
| Haili Page | Zoe |
| Scott Heindl | Gedge |
| James Remar | Ray Cumberland |
| Kris Kristofferson | Abraham Whistler |
| Dominic Purcell | Drake |
| Mark Berry | Chief Martin Vreede |
| John Michael Higgins | Dr. Edgar Vance |
| Callum Keith Rennie | Asher Talos |
| Paul Levesque | Jarko Grimwood |
| Paul Anthony | Wolfe |
| Françoise Yip | Virago |
| Michael Rawlins | Wilson Hale |
| Paul Wu | Ellingson |